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Ni(2+)-Assisted Hydrolysis May Affect the Human Proteome; Filaggrin Degradation Ex Vivo as an Example of Possible Consequences
Deficiency in a principal epidermal barrier protein, filaggrin (FLG), is associated with multiple allergic manifestations, including atopic dermatitis and contact allergy to nickel. Toxicity caused by dermal and respiratory exposures of the general population to nickel-containing objects and particl...
Autores principales: | Podobas, Ewa Izabela, Gutowska-Owsiak, Danuta, Moretti, Sébastien, Poznański, Jarosław, Kulińczak, Mariusz, Grynberg, Marcin, Gruca, Aleksandra, Bonna, Arkadiusz, Płonka, Dawid, Frączyk, Tomasz, Ogg, Graham, Bal, Wojciech |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960189/ https://www.ncbi.nlm.nih.gov/pubmed/35359602 http://dx.doi.org/10.3389/fmolb.2022.828674 |
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