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Ni(2+)-Assisted Hydrolysis May Affect the Human Proteome; Filaggrin Degradation Ex Vivo as an Example of Possible Consequences

Deficiency in a principal epidermal barrier protein, filaggrin (FLG), is associated with multiple allergic manifestations, including atopic dermatitis and contact allergy to nickel. Toxicity caused by dermal and respiratory exposures of the general population to nickel-containing objects and particl...

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Detalles Bibliográficos
Autores principales: Podobas, Ewa Izabela, Gutowska-Owsiak, Danuta, Moretti, Sébastien, Poznański, Jarosław, Kulińczak, Mariusz, Grynberg, Marcin, Gruca, Aleksandra, Bonna, Arkadiusz, Płonka, Dawid, Frączyk, Tomasz, Ogg, Graham, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960189/
https://www.ncbi.nlm.nih.gov/pubmed/35359602
http://dx.doi.org/10.3389/fmolb.2022.828674

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