Observation versus screening spinal MRI and pre-emptive treatment for spinal cord compression in patients with castration-resistant prostate cancer and spinal metastases in the UK (PROMPTS): an open-label, randomised, controlled, phase 3 trial

BACKGROUND: Early diagnosis of malignant spinal cord compression (SCC) is crucial because pretreatment neurological status is the major determinant of outcome. In metastatic castration-resistant prostate cancer, SCC is a clinically significant cause of disease-related morbidity and mortality. We inv...

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Detalles Bibliográficos
Autores principales: Dearnaley, David, Hinder, Victoria, Hijab, Adham, Horan, Gail, Srihari, Narayanan, Rich, Philip, Houston, J Graeme, Henry, Ann M, Gibbs, Stephanie, Venkitaraman, Ram, Cruickshank, Clare, Hassan, Shama, Miners, Alec, Mason, Malcolm, Pedley, Ian, Payne, Heather, Brock, Susannah, Wade, Robert, Robinson, Angus, Din, Omar, Lees, Kathryn, Graham, John, Worlding, Jane, Murray, Julia, Parker, Chris, Griffin, Clare, Sohaib, Aslam, Hall, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960282/
https://www.ncbi.nlm.nih.gov/pubmed/35279270
http://dx.doi.org/10.1016/S1470-2045(22)00092-4

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