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Cardiorespiratory physiology, exertional symptoms, and psychological burden in post-COVID-19 fatigue

Fatigue is a common, debilitating, and poorly understood symptom post-COVID-19. We sought to better characterize differences in those with and without post-COVID-19 fatigue using cardiopulmonary exercise testing. Despite elevated dyspnoea intensity ratings, V̇O(2)peak (ml/kg/min) was the only signif...

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Detalles Bibliográficos
Autores principales: Schaeffer, Michele R., Cowan, Juthaporn, Milne, Kathryn M., Puyat, Joseph H., Voduc, Nha, Corrales-Medina, Vicente, Lavoie, Kim L., Mulloy, Andrew, Chirinos, Julio A., Abdallah, Sara J., Guenette, Jordan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960286/
https://www.ncbi.nlm.nih.gov/pubmed/35364291
http://dx.doi.org/10.1016/j.resp.2022.103898
Descripción
Sumario:Fatigue is a common, debilitating, and poorly understood symptom post-COVID-19. We sought to better characterize differences in those with and without post-COVID-19 fatigue using cardiopulmonary exercise testing. Despite elevated dyspnoea intensity ratings, V̇O(2)peak (ml/kg/min) was the only significant difference in the physiological responses to exercise (19.9 ± 7.1 fatigue vs. 24.4 ± 6.7 ml/kg/min non-fatigue, p = 0.04). Consistent with previous findings, we also observed a higher psychological burden in those with fatigue in the context of similar resting cardiopulmonary function. Our findings suggest that lower cardiorespiratory fitness and/or psychological factors may contribute to post-COVID-19 fatigue symptomology. Further research is needed for rehabilitation and symptom management following SARS-CoV-2 infection.