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Atrial Lesions in a Pedigree With PRKAG2 Cardiomyopathy: Involvement of Disrupted AMP-Activated Protein Kinase Signaling
PRKAG2 cardiomyopathy is a rare progressive disease characterized by increased ventricular wall thickness and preexcitation. Dysfunction of the protein 5′-AMP-activated protein kinase (AMPK) plays a decisive role in the progression of ventricular lesions. Although patients with the PRKAG2-R302Q muta...
Autores principales: | Chen, Shaojie, Lin, Yongping, Zhu, Yue, Geng, Le, Cui, Chang, Li, Zhaomin, Liu, Hailei, Chen, Hongwu, Ju, Weizhu, Chen, Minglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960295/ https://www.ncbi.nlm.nih.gov/pubmed/35360035 http://dx.doi.org/10.3389/fcvm.2022.840337 |
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