Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming

BACKGROUND: Lymph node metastasis (LNM) commonly occurs in gastric cancer (GC) and is tightly associated with poor prognosis. Exosome-mediated lymphangiogenesis has been considered an important driver of LNM. Whether exosomes directly transmit the LNM phenotype between GC cells and its mechanisms re...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Yu, Wanjun, Cao, Xiaoli, Gu, Hongbing, Huang, Jiaying, Wu, Chen, Wang, Lin, Sha, Xin, Shen, Bo, Wang, Ting, Yao, Yongliang, Zhu, Wei, Huang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960311/
https://www.ncbi.nlm.nih.gov/pubmed/35359362
http://dx.doi.org/10.3389/fonc.2022.860175

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