A Nanobody-Based Toolset to Monitor and Modify the Mitochondrial GTPase Miro1

The mitochondrial outer membrane (MOM)-anchored GTPase Miro1, is a central player in mitochondrial transport and homeostasis. The dysregulation of Miro1 in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) suggests that Miro1 may be a potential biomarker or drug target in neuronal dis...

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Detalles Bibliográficos
Autores principales: Fagbadebo, Funmilayo O., Kaiser, Philipp D., Zittlau, Katharina, Bartlick, Natascha, Wagner, Teresa R., Froehlich, Theresa, Jarjour, Grace, Nueske, Stefan, Scholz, Armin, Traenkle, Bjoern, Macek, Boris, Rothbauer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960383/
https://www.ncbi.nlm.nih.gov/pubmed/35359597
http://dx.doi.org/10.3389/fmolb.2022.835302

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