Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor

The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor (NMDAR) antagonist (R,S)-ketamine has been a crucial breakthrough in mood disorder research. (R,S)-ketamine is a racemic mixture of equal amounts of (R)-ketamine (arketamine) and (S)-ketamine (esketamine). In...

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Detalles Bibliográficos
Autores principales: Wei, Yan, Chang, Lijia, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Expert Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960399/
https://www.ncbi.nlm.nih.gov/pubmed/33963284
http://dx.doi.org/10.1038/s41380-021-01121-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960399/
https://www.ncbi.nlm.nih.gov/pubmed/33963284
http://dx.doi.org/10.1038/s41380-021-01121-1

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