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Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor
The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor (NMDAR) antagonist (R,S)-ketamine has been a crucial breakthrough in mood disorder research. (R,S)-ketamine is a racemic mixture of equal amounts of (R)-ketamine (arketamine) and (S)-ketamine (esketamine). In...
Autores principales: | Wei, Yan, Chang, Lijia, Hashimoto, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960399/ https://www.ncbi.nlm.nih.gov/pubmed/33963284 http://dx.doi.org/10.1038/s41380-021-01121-1 |
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