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Update on GPCR-based targets for the development of novel antidepressants

Traditional antidepressants largely interfere with monoaminergic transport or degradation systems, taking several weeks to have their therapeutic actions. Moreover, a large proportion of depressed patients are resistant to these therapies. Several atypical antidepressants have been developed which i...

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Detalles Bibliográficos
Autores principales: Mantas, Ioannis, Saarinen, Marcus, Xu, Zhi-Qing David, Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960420/
https://www.ncbi.nlm.nih.gov/pubmed/33589739
http://dx.doi.org/10.1038/s41380-021-01040-1