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GMMA Technology for the Development of Safe Vaccines: Meta-Analysis of Individual Patient Data to Assess the Safety Profile of Shigella sonnei 1790GAHB Vaccine in Healthy Adults, with Special Focus on Neutropenia
INTRODUCTION: Shigellosis is a major health concern among children < 5 years of age from developing countries, and there are no widely available vaccines to prevent it. The GMMA-based 1790GAHB investigational vaccine against Shigella sonnei was well tolerated and immunogenic in phase 1 and 2 stud...
Autores principales: | De Ryck, Iris, Sarakinou, Eleanna, Nakakana, Usman, Cilio, Giulia Luna, Ndiaye, Augustin, Vella, Venanzio, Auerbach, Joachim, Granada, Juan-Paolo, Conti, Valentino, Podda, Audino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960504/ https://www.ncbi.nlm.nih.gov/pubmed/35118580 http://dx.doi.org/10.1007/s40121-022-00596-x |
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