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Essential role of a conserved aspartate for the enzymatic activity of plasmanylethanolamine desaturase

Plasmalogens are an abundant class of glycerophospholipids in the mammalian body, with special occurrence in the brain and in immune cell membranes. Plasmanylethanolamine desaturase (PEDS1) is the final enzyme of plasmalogen biosynthesis, which introduces the characteristic 1-O-alk-1′-enyl double bo...

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Detalles Bibliográficos
Autores principales:	Werner, Ernst R., Fernández-Quintero, Monica L., Hulo, Nicolas, Golderer, Georg, Sailer, Sabrina, Lackner, Katharina, Werner-Felmayer, Gabriele, Liedl, Klaus R., Watschinger, Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960569/ https://www.ncbi.nlm.nih.gov/pubmed/35347434 http://dx.doi.org/10.1007/s00018-022-04238-w

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