Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS. Given that astrocytes make specialised contacts with some synapses, called tripartite synapses, we hyp...

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Detalles Bibliográficos
Autores principales: Broadhead, Matthew J., Bonthron, Calum, Waddington, Julia, Smith, William V., Lopez, Maite F., Burley, Sarah, Valli, Jessica, Zhu, Fei, Komiyama, Noboru H., Smith, Colin, Grant, Seth G. N., Miles, Gareth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960590/
https://www.ncbi.nlm.nih.gov/pubmed/35305541
http://dx.doi.org/10.1007/s00401-022-02412-9

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