Cargando…
Inhibition of Anti-Inflammatory Macrophage Phenotype Reduces Tumour Growth in Mouse Models of Brain Metastasis
Breast cancer brain metastasis is a significant clinical problem and carries a poor prognosis. Although it is well-established that macrophages are a primary component of the brain metastasis microenvironment, the role of blood-derived macrophages (BDM) and brain-resident microglia in the progressio...
Autores principales: | Economopoulos, Vasiliki, Pannell, Maria, Johanssen, Vanessa A., Scott, Helen, Andreou, Kleopatra E., Larkin, James R., Sibson, Nicola R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960618/ https://www.ncbi.nlm.nih.gov/pubmed/35359423 http://dx.doi.org/10.3389/fonc.2022.850656 |
Ejemplares similares
-
Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis
por: Andreou, Kleopatra E., et al.
Publicado: (2017) -
Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
por: Pannell, Maria, et al.
Publicado: (2019) -
Improving Delineation of True Tumor Volume With Multimodal MRI in a Rat Model of Brain Metastasis
por: Larkin, James R., et al.
Publicado: (2020) -
A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models
por: Zarghami, Niloufar, et al.
Publicado: (2020) -
Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth
por: Soto, Manuel Sarmiento, et al.
Publicado: (2016)