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Initiation and progression of α-synuclein pathology in Parkinson’s disease
α-Synuclein aggregation is a critical molecular process that underpins the pathogenesis of Parkinson’s disease. Aggregates may originate at synaptic terminals as a consequence of aberrant interactions between α-synuclein and lipids or evasion of proteostatic defences. The nature of these interaction...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960654/ https://www.ncbi.nlm.nih.gov/pubmed/35347432 http://dx.doi.org/10.1007/s00018-022-04240-2 |