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Rekombinante Antikörper als Alternativen in Forschung und Diagnostik

Despite readily available alternative technologies, many antibodies in research and diagnostics are still generated and produced with the use of laboratory animals. Here, we portrait the concept of animal-free recombinant antibodies and the generation of such an antibody against the spike-protein of...

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Detalles Bibliográficos
Autores principales: Wenzel, Esther Veronika, Zilkens, Kilian Johannes Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960684/
https://www.ncbi.nlm.nih.gov/pubmed/35369108
http://dx.doi.org/10.1007/s12268-022-1716-7
Descripción
Sumario:Despite readily available alternative technologies, many antibodies in research and diagnostics are still generated and produced with the use of laboratory animals. Here, we portrait the concept of animal-free recombinant antibodies and the generation of such an antibody against the spike-protein of SARS-Cov-2. The scientific community needs to raise awareness for more sustainable animal-free alternatives, especially as they offer a path to more reliable and reproducible data.