Feasibility, pitfalls and results of a structured concept-development phase for a randomized controlled phase III trial on radiotherapy in primary prostate cancer patients

OBJECTIVE: Failure rate in randomized controlled trials (RCTs) is > 50%, includes safety-problems, underpowered statistics, lack of efficacy, lack of funding or insufficient patient recruitment and is even more pronounced in oncology trials. We present results of a structured concept-development...

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Detalles Bibliográficos
Autores principales: Spohn, S. K. B., Adebahr, S., Huber, M., Jenkner, C., Wiehle, R., Nagavci, B., Schmucker, C., Carl, E. G., Chen, R. C., Weber, W. A., Mix, M., Rühle, A., Sprave, T., Nicolay, N. H., Gratzke, C., Benndorf, M., Wiegel, T., Weis, J., Baltas, D., Grosu, A. L., Zamboglou, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960686/
https://www.ncbi.nlm.nih.gov/pubmed/35351058
http://dx.doi.org/10.1186/s12885-022-09434-2

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