Cargando…

Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells

Lung cancer is the second most common cancer worldwide and the leading cause of cancer death in the world. Therefore, there is an urgent need to develop new and effective biomarkers for diagnosis and treatment. Under this circumstance, human endogenous retroviruses (HERVs) were recently introduced a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Caiqin, Guo, Xin, Li, Jianjie, Han, Jingwan, Jia, Lei, Wen, Hong-Ling, Sun, Chengxi, Wang, Xiaolin, Zhang, Bohan, Li, Jingyun, Chi, Yujia, An, Tongtong, Wang, Yuyan, Wang, Ziping, Li, Hanping, Li, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960717/ https://www.ncbi.nlm.nih.gov/pubmed/35359739 http://dx.doi.org/10.3389/fmicb.2022.850444

Ejemplares similares

Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
por: Kang, Qian, et al.
Publicado: (2023)

Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
por: Jia, Lei, et al.
Publicado: (2022)

High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients
por: Guo, Yaolin, et al.
Publicado: (2022)

Ancient Adversary – HERV-K (HML-2) in Cancer
por: Dervan, Eoin, et al.
Publicado: (2021)

p53 Binding Sites in Long Terminal Repeat 5Hs (LTR5Hs) of Human Endogenous Retrovirus K Family (HML-2 Subgroup) Play Important Roles in the Regulation of LTR5Hs Transcriptional Activity
por: Liu, Mengying, et al.
Publicado: (2022)

Exploring HERV-K (HML-2) Influence in Cancer and Prospects for Therapeutic Interventions
por: Costa, Bárbara, et al.
Publicado: (2023)

HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease
por: Hohn, Oliver, et al.
Publicado: (2013)

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
por: Mayer, Jens, et al.
Publicado: (2018)

Infection by Diverse HIV-1 Subtypes Leads to Different Elevations in HERV-K Transcriptional Levels in Human T Cell Lines
por: Li, Xi, et al.
Publicado: (2021)

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers
por: de Mulder, Miguel, et al.
Publicado: (2017)

Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2022)

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
por: Grandi, Nicole, et al.
Publicado: (2020)

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma
por: Schmitt, Katja, et al.
Publicado: (2013)

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
por: Broecker, Felix, et al.
Publicado: (2016)

Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
por: Burn, Aidan, et al.
Publicado: (2022)

Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
por: Scognamiglio, Sante, et al.
Publicado: (2022)

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project
por: Flockerzi, Aline, et al.
Publicado: (2008)

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element
por: George, Maja, et al.
Publicado: (2011)

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
por: Subramanian, Ravi P, et al.
Publicado: (2011)

Preferential expression of human endogenous retrovirus K (HERV-K/HML-2) type 1 in tumor cells
por: Romano, Camila M, et al.
Publicado: (2011)

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1
por: Bhardwaj, Neeru, et al.
Publicado: (2015)

Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22
por: Autio, Arttu, et al.
Publicado: (2020)

Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients
por: Shah, Ashish H., et al.
Publicado: (2022)

HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates
por: Grandi, Nicole, et al.
Publicado: (2021)

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion
por: Grandi, Nicole, et al.
Publicado: (2017)

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues
por: Schmitt, Katja, et al.
Publicado: (2015)

Increased HERV-K(HML-2) Transcript Levels Correlate with Clinical Parameters of Liver Damage in Hepatitis C Patients
por: Weber, Melanie, et al.
Publicado: (2021)

Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
por: Chabukswar, Saili, et al.
Publicado: (2022)

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)
por: Hohn, Oliver, et al.
Publicado: (2014)

Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Correction to: Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Expression of Human Endogenous Retrovirus Group K (HERV-K) HML-2 Correlates with Immune Activation of Macrophages and Type I Interferon Response
por: Russ, Eric, et al.
Publicado: (2023)

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec
por: Ruggieri, Alessia, et al.
Publicado: (2009)

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection
por: Michaud, Henri-Alexandre, et al.
Publicado: (2014)

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites
por: Montesion, Meagan, et al.
Publicado: (2018)

A Comprehensive Analysis of Human Endogenous Retroviruses HERV-K (HML.2) from Teratocarcinoma Cell Lines and Detection of Viral Cargo in Microvesicles
por: Morozov, Vladimir A., et al.
Publicado: (2021)

Human endogenous retroviruses of the HERV-K (HML-2) family are expressed in the brain of healthy individuals and modify the composition of the brain-infiltrating immune cells
por: Nevalainen, Tapio, et al.
Publicado: (2023)

Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains
por: Liu, Yongjian, et al.
Publicado: (2020)

Is the HERV-K HML-2 Xq21.33, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?
por: Kaplan, Mark H., et al.
Publicado: (2020)

Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies
por: Macfarlane, Catriona M, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e7tofv23u5sj1llfkccomp6q2u