Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons

Numerous studies have shown a strong correlation between the number of neurofibrillary tangles of the tau protein and Alzheimer's disease progression, making the quantitative detection of tau very promising from a clinical point of view. However, the lack of highly reliable fluorescent probes f...

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Detalles Bibliográficos
Autores principales: Soloperto, Alessandro, Quaglio, Deborah, Baiocco, Paola, Romeo, Isabella, Mori, Mattia, Ardini, Matteo, Presutti, Caterina, Sannino, Ida, Ghirga, Silvia, Iazzetti, Antonia, Ippoliti, Rodolfo, Ruocco, Giancarlo, Botta, Bruno, Ghirga, Francesca, Di Angelantonio, Silvia, Boffi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960764/
https://www.ncbi.nlm.nih.gov/pubmed/35347170
http://dx.doi.org/10.1038/s41598-022-09016-z

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