Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by performing single-cell RNA sequencing on 144,878 cells from 14 pairs of iCCA tumors and non-tumor liver tissues, we find that S100P and SPP1 a...

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Detalles Bibliográficos
Autores principales: Song, Guohe, Shi, Yang, Meng, Lu, Ma, Jiaqiang, Huang, Siyuan, Zhang, Juan, Wu, Yingcheng, Li, Jiaxin, Lin, Youpei, Yang, Shuaixi, Rao, Dongning, Cheng, Yifei, Lin, Jian, Ji, Shuyi, Liu, Yuming, Jiang, Shan, Wang, Xiaoliang, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Ji, Yuan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960779/
https://www.ncbi.nlm.nih.gov/pubmed/35347134
http://dx.doi.org/10.1038/s41467-022-29164-0

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