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GRP78 blockade overcomes intrinsic resistance to UBA1 inhibitor TAK-243 in glioblastoma

Glioblastoma multiforme (GBM) is the most aggressive malignant primary brain tumor of the central nervous system. Despite continuous progression in treatment options for GBM like surgery, radiotherapy, and chemotherapy, this disease still has a high rate of recurrence. The endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales:	Zhang, Xu, Wu, Runqiu, Tian, Cong, Wang, Wanzhou, Zhou, Lingni, Guo, Tongxuan, Yu, Jiefeng, Wu, Changyong, Shen, Yang, Liu, Xuejiao, Yu, Rutong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960808/ https://www.ncbi.nlm.nih.gov/pubmed/35347123 http://dx.doi.org/10.1038/s41420-022-00950-5

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