Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors

Chemoimmunotherapy has recently failed to demonstrate significant clinical benefit in advanced bladder cancer patients; and the mechanism(s) underlying such suboptimal response remain elusive. To date, most studies have focused on tumor-intrinsic properties that render them “immune-excluded”. Here,...

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Detalles Bibliográficos
Autores principales: Nikolos, Fotis, Hayashi, Kazukuni, Hoi, Xen Ping, Alonzo, Mark Ellie, Mo, Qianxing, Kasabyan, Armine, Furuya, Hideki, Trepel, Jane, Di Vizio, Dolores, Guarnerio, Jlenia, Theodorescu, Dan, Rosser, Charles, Apolo, Andrea, Galsky, Matthew, Chan, Keith Syson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960844/
https://www.ncbi.nlm.nih.gov/pubmed/35347124
http://dx.doi.org/10.1038/s41467-022-29026-9

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