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Aging-Related Alterations of Glymphatic Transport in Rat: In vivo Magnetic Resonance Imaging and Kinetic Study

OBJECTIVE: Impaired glymphatic waste clearance function during brain aging leads to the accumulation of metabolic waste and neurotoxic proteins (e.g., amyloid-β, tau) which contribute to neurological disorders. However, how the age-related glymphatic dysfunction exerts its effects on different cereb...

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Detalles Bibliográficos
Autores principales: Li, Lian, Ding, Guangliang, Zhang, Li, Davoodi-Bojd, Esmaeil, Chopp, Michael, Li, Qingjiang, Zhang, Zheng Gang, Jiang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960847/
https://www.ncbi.nlm.nih.gov/pubmed/35360203
http://dx.doi.org/10.3389/fnagi.2022.841798