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Correlational networking guides the discovery of unclustered lanthipeptide protease-encoding genes
Bacterial natural product biosynthetic genes, canonically clustered, have been increasingly found to rely on hidden enzymes encoded elsewhere in the genome for completion of biosynthesis. The study and application of lanthipeptides are frequently hindered by unclustered protease genes required for f...
Autores principales: | Xue, Dan, Older, Ethan A., Zhong, Zheng, Shang, Zhuo, Chen, Nanzhu, Dittenhauser, Nolan, Hou, Lukuan, Cai, Peiyan, Walla, Michael D., Dong, Shi-Hui, Tang, Xiaoyu, Chen, Hexin, Nagarkatti, Prakash, Nagarkatti, Mitzi, Li, Yong-Xin, Li, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960859/ https://www.ncbi.nlm.nih.gov/pubmed/35347143 http://dx.doi.org/10.1038/s41467-022-29325-1 |
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