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The Screen of a Phage Display Library Identifies a Peptide That Binds to the Surface of Trypanosoma cruzi Trypomastigotes and Impairs Their Infection of Mammalian Cells

BACKGROUND: Chagas is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. On the order of seven million people are infected worldwide and current therapies are limited, highlighting the urgent need for new interventions. T. cruzi trypomastigotes can infect a variety of m...

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Detalles Bibliográficos
Autores principales: de Paula, Jéssica I., Lopes-Torres, Eduardo J., Jacobs-Lorena, Marcelo, Paes, Marcia Cristina, Cha, Sung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960960/
https://www.ncbi.nlm.nih.gov/pubmed/35359712
http://dx.doi.org/10.3389/fmicb.2022.864788