Cargando…
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma
BACKGROUND: Immune checkpoint blockade (ICB) targeting programmed death ligand-1 (PD-L1)/programmed cell death protein-1 (PD-1) pathway has become an attractive strategy for cancer treatment; however, unsatisfactory efficacy has limited its clinical benefits. Therefore, a more comprehensive understa...
Autores principales: | Chen, Xisha, Wang, Kuansong, Jiang, Shilong, Sun, Hongyin, Che, Xuanling, Zhang, Minghui, He, Jiaying, Wen, Ying, Liao, Mengting, Li, Xiangling, Zhou, Xiaoming, Song, Jianxun, Ren, Xingcong, Yi, Wenjun, Yang, Jinming, Chen, Xiang, Yin, Mingzhu, Cheng, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961175/ https://www.ncbi.nlm.nih.gov/pubmed/35347072 http://dx.doi.org/10.1136/jitc-2021-004026 |
Ejemplares similares
-
Combined treatment of mitoxantrone sensitizes breast cancer cells to rapalogs through blocking eEF-2K-mediated activation of Akt and autophagy
por: Guan, Yidi, et al.
Publicado: (2020) -
Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy
por: Sun, Guangshun, et al.
Publicado: (2022) -
Depicting the landscape of gut microbial-metabolic interaction and microbial-host immune heterogeneity in deficient and proficient DNA mismatch repair colorectal cancers
por: Li, Jinming, et al.
Publicado: (2023) -
Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer
por: Sui, Qiaoqi, et al.
Publicado: (2021) -
Non-invasive CT imaging biomarker to predict immunotherapy response in gastric cancer: a multicenter study
por: Huang, Weicai, et al.
Publicado: (2023)