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Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer

BACKGROUND: Tumor-associated macrophages (TAMs) secreting IL-10 could be a specific functional cell subset with distinct polarization state and suppressive role in antitumor immune response. Here, we assessed the associations of clinical outcome, therapeutic responses and molecular features with IL-...

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Detalles Bibliográficos
Autores principales:	Xu, Yijia, Zeng, Han, Jin, Kaifeng, Liu, Zhaopei, Zhu, Yu, Xu, Le, Wang, Zewei, Chang, Yuan, Xu, Jiejie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961180/ https://www.ncbi.nlm.nih.gov/pubmed/35338085 http://dx.doi.org/10.1136/jitc-2021-003416

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