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P2X7 receptor induces microglia polarization to the M1 phenotype in cancer-induced bone pain rat models

BACKGROUND: The transition from pro-inflammatory M1 phenotype to anti-inflammatory M2 phenotype presents a novel therapeutic strategy for chronic pain. OBJECTIVE: We investigated the role of microglia polarization in cancer-induced bone pain (CIBP), as well as the role of the P2X7 receptor in modula...

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Detalles Bibliográficos
Autores principales:	Wu, Ping, Zhou, Guohua, Wu, Xiaoqi, Lv, Run, Yao, Jiaqi, Wen, Qingping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961217/ https://www.ncbi.nlm.nih.gov/pubmed/35057643 http://dx.doi.org/10.1177/17448069211060962

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