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Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice

Angiotensin-converting enzyme 2 (ACE2) is the established cellular receptor for SARS-CoV-2. However, it is unclear whether ACE1 inhibitors (e.g., lisinopril) or angiotensin receptor blockers (e.g., losartan) alter tissue ACE2 expression. This study sought to determine whether lisinopril or losartan,...

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Detalles Bibliográficos
Autores principales:	Brooks, Steven D., Smith, Rachel L., Moreira, Aline S., Ackerman, Hans C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961328/ https://www.ncbi.nlm.nih.gov/pubmed/35359831 http://dx.doi.org/10.3389/fphar.2022.798349

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