Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child

We describe a unique clinical presentation of a child after the acute phase of herpes simplex virus 1 (HSV1) encephalitis. A 17-month-old boy first presented with HSV1 encephalitis and was promptly treated with antiviral medication. Seven months later, he was re-admitted for startle seizures. Magnet...

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Autores principales: Ng, Andy Cheuk-Him, Kassiri, Janani, Goez, Helly R., Morneau-Jacob, Francois, Mailo, Janette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961350/
https://www.ncbi.nlm.nih.gov/pubmed/35360486
http://dx.doi.org/10.1177/2329048X221083761
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author Ng, Andy Cheuk-Him
Kassiri, Janani
Goez, Helly R.
Morneau-Jacob, Francois
Mailo, Janette
author_facet Ng, Andy Cheuk-Him
Kassiri, Janani
Goez, Helly R.
Morneau-Jacob, Francois
Mailo, Janette
author_sort Ng, Andy Cheuk-Him
collection PubMed
description We describe a unique clinical presentation of a child after the acute phase of herpes simplex virus 1 (HSV1) encephalitis. A 17-month-old boy first presented with HSV1 encephalitis and was promptly treated with antiviral medication. Seven months later, he was re-admitted for startle seizures. Magnetic Resonance Imaging of the brain showed diffuse confluent leukoencephalopathy. This constellation of symptoms has not been previously reported in HSV1 encephalitis. In conclusion, we showed that brain injury due to HSV1 encephalitis can be associated with the development of startle seizures and diffuse white matter injury in the post-acute phase.
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spelling pubmed-89613502022-03-30 Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child Ng, Andy Cheuk-Him Kassiri, Janani Goez, Helly R. Morneau-Jacob, Francois Mailo, Janette Child Neurol Open Case Report We describe a unique clinical presentation of a child after the acute phase of herpes simplex virus 1 (HSV1) encephalitis. A 17-month-old boy first presented with HSV1 encephalitis and was promptly treated with antiviral medication. Seven months later, he was re-admitted for startle seizures. Magnetic Resonance Imaging of the brain showed diffuse confluent leukoencephalopathy. This constellation of symptoms has not been previously reported in HSV1 encephalitis. In conclusion, we showed that brain injury due to HSV1 encephalitis can be associated with the development of startle seizures and diffuse white matter injury in the post-acute phase. SAGE Publications 2022-03-24 /pmc/articles/PMC8961350/ /pubmed/35360486 http://dx.doi.org/10.1177/2329048X221083761 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Ng, Andy Cheuk-Him
Kassiri, Janani
Goez, Helly R.
Morneau-Jacob, Francois
Mailo, Janette
Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title_full Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title_fullStr Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title_full_unstemmed Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title_short Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child
title_sort startle seizures and diffuse leukoencephalopathy after resolution of herpes simplex virus 1 encephalitis in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961350/
https://www.ncbi.nlm.nih.gov/pubmed/35360486
http://dx.doi.org/10.1177/2329048X221083761
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