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Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis
Osteoarthritis is a prevalent degenerative disease affecting a large portion of the world’s aging population. Currently, nonsteroidal anti-inflammatory drugs and acetaminophen are first-line medications for treating osteoarthritis patients’ pain. However, several studies have noted that while these...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961370/ https://www.ncbi.nlm.nih.gov/pubmed/35360183 http://dx.doi.org/10.1177/11795441211063365 |
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author | Bharat, Krish Tejas Manhas, Navdeep Singh Gutcho, James Lin, Joshua Bhattacharyya, Sumon Kounang, Robertus |
author_facet | Bharat, Krish Tejas Manhas, Navdeep Singh Gutcho, James Lin, Joshua Bhattacharyya, Sumon Kounang, Robertus |
author_sort | Bharat, Krish Tejas |
collection | PubMed |
description | Osteoarthritis is a prevalent degenerative disease affecting a large portion of the world’s aging population. Currently, nonsteroidal anti-inflammatory drugs and acetaminophen are first-line medications for treating osteoarthritis patients’ pain. However, several studies have noted that while these medications control pain they do not halt progressive degeneration and tend to have an unfavorable side-effect profile with prolonged use. Recently, due to their more favorable side-effect profiles, herbal alternatives for controlling osteoarthritis symptoms and for alleviating the progression of the disease are being increasingly studied. Synogesic is a newly developed herbal supplement blend by renowned orthopedic surgeons and physiatrists consisting of turmeric, rutin, ginger root, vitamin C, vitamin D, and boswellia extracts. A study by Sharkey et al. has commented on the efficacy of the blend on the patients with knee osteoarthritis. So far, a review on the ingredients of the blend has not yet carried outbeen. By exploring prominent literature databases including PubMed and ScienceDirect, our aim is to write a narrative review to explore the individual ingredients of this blend and delve into their characteristics, as well as the most recent literature on their mechanism and efficacy in patients with osteoarthritis. Through this, we hope to inform clinicians and patients alike on relevant up-to-date research on the supplement and provide insight on the potential for this supplement for alleviating the disease course of patients with osteoarthritis. |
format | Online Article Text |
id | pubmed-8961370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-89613702022-03-30 Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis Bharat, Krish Tejas Manhas, Navdeep Singh Gutcho, James Lin, Joshua Bhattacharyya, Sumon Kounang, Robertus Clin Med Insights Arthritis Musculoskelet Disord Review Osteoarthritis is a prevalent degenerative disease affecting a large portion of the world’s aging population. Currently, nonsteroidal anti-inflammatory drugs and acetaminophen are first-line medications for treating osteoarthritis patients’ pain. However, several studies have noted that while these medications control pain they do not halt progressive degeneration and tend to have an unfavorable side-effect profile with prolonged use. Recently, due to their more favorable side-effect profiles, herbal alternatives for controlling osteoarthritis symptoms and for alleviating the progression of the disease are being increasingly studied. Synogesic is a newly developed herbal supplement blend by renowned orthopedic surgeons and physiatrists consisting of turmeric, rutin, ginger root, vitamin C, vitamin D, and boswellia extracts. A study by Sharkey et al. has commented on the efficacy of the blend on the patients with knee osteoarthritis. So far, a review on the ingredients of the blend has not yet carried outbeen. By exploring prominent literature databases including PubMed and ScienceDirect, our aim is to write a narrative review to explore the individual ingredients of this blend and delve into their characteristics, as well as the most recent literature on their mechanism and efficacy in patients with osteoarthritis. Through this, we hope to inform clinicians and patients alike on relevant up-to-date research on the supplement and provide insight on the potential for this supplement for alleviating the disease course of patients with osteoarthritis. SAGE Publications 2022-03-25 /pmc/articles/PMC8961370/ /pubmed/35360183 http://dx.doi.org/10.1177/11795441211063365 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Bharat, Krish Tejas Manhas, Navdeep Singh Gutcho, James Lin, Joshua Bhattacharyya, Sumon Kounang, Robertus Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis |
title | Ingredients of a Natural Oral Nutritional Supplement and Their Role
in the Treatment of Osteoarthritis |
title_full | Ingredients of a Natural Oral Nutritional Supplement and Their Role
in the Treatment of Osteoarthritis |
title_fullStr | Ingredients of a Natural Oral Nutritional Supplement and Their Role
in the Treatment of Osteoarthritis |
title_full_unstemmed | Ingredients of a Natural Oral Nutritional Supplement and Their Role
in the Treatment of Osteoarthritis |
title_short | Ingredients of a Natural Oral Nutritional Supplement and Their Role
in the Treatment of Osteoarthritis |
title_sort | ingredients of a natural oral nutritional supplement and their role
in the treatment of osteoarthritis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961370/ https://www.ncbi.nlm.nih.gov/pubmed/35360183 http://dx.doi.org/10.1177/11795441211063365 |
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