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Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in osteoporosis microenvironment

To solve the issue of unsatisfactory recruitment of mesenchymal stem cells (MSCs) around implant in osteoporotic fractures, we fabricated a ROS-responsive system on titanium surface through hydroxyapatite coating and biomolecule grafting. The porous hydroxyapatite and phosphorylated osteogenic growt...

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Detalles Bibliográficos
Autores principales: Chen, Maohua, Sun, Yuting, Hou, Yanhua, Luo, Zhong, Li, Menghuan, Wei, Yujia, Chen, Maowen, Tan, Lu, Cai, Kaiyong, Hu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961459/
https://www.ncbi.nlm.nih.gov/pubmed/35387165
http://dx.doi.org/10.1016/j.bioactmat.2022.02.006