Cargando…

Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative

In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer agents. X-ray investigations for 1-(2,4-dichlorophenoxy)acetyl-4-(2-fluorophenyl) thiosemicarbazide, 1-(2,4-dichlorophenoxy)acetyl-4-(4-metylothiophenyl)thiosemicarbazide and 1-(2,4-di chlorophenoxy)acetyl-4-(4-iod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kozyra, Paweł, Korga-Plewko, Agnieszka, Karczmarzyk, Zbigniew, Hawrył, Anna, Wysocki, Waldemar, Człapski, Michał, Iwan, Magdalena, Ostrowska-Leśko, Marta, Fornal, Emilia, Pitucha, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961551/ https://www.ncbi.nlm.nih.gov/pubmed/35204651 http://dx.doi.org/10.3390/biom12020151

Ejemplares similares

2,4-Dichlorophenoxyacetic Thiosemicarbazides as a New Class of Compounds against Stomach Cancer Potentially Intercalating with DNA †
por: Pitucha, Monika, et al.
Publicado: (2020)

Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells
por: Pitucha, Monika, et al.
Publicado: (2021)

Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents
por: Pitucha, Monika, et al.
Publicado: (2019)

Retention Behavior of Anticancer Thiosemicarbazides in Biomimetic Chromatographic Systems and In Silico Calculations
por: Studziński, Marek, et al.
Publicado: (2023)

Lipophilicity Studies on Thiosemicarbazide Derivatives
por: Paneth, Agata, et al.
Publicado: (2017)

Ethyl 2-(3-methyl-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-4-yl)acetate
por: Karczmarzyk, Zbigniew, et al.
Publicado: (2012)

3-Benzyl-4-ethyl-1H-1,2,4-triazole-5(4H)-thione
por: Karczmarzyk, Zbigniew, et al.
Publicado: (2013)

Apigenin and Hesperidin Downregulate DNA Repair Genes in MCF-7 Breast Cancer Cells and Augment Doxorubicin Toxicity
por: Korga-Plewko, Agnieszka, et al.
Publicado: (2020)

Hyaluronic Acid as a Modern Approach in Anticancer Therapy-Review
por: Michalczyk, Monika, et al.
Publicado: (2022)

New Application of 1,2,4-Triazole Derivatives as Antitubercular Agents. Structure, In Vitro Screening and Docking Studies
por: Karczmarzyk, Zbigniew, et al.
Publicado: (2020)

New Potential Agents for Malignant Melanoma Treatment—Most Recent Studies 2020–2022
por: Kozyra, Paweł, et al.
Publicado: (2022)

1,3-Dimethyl-5-methylsulfonyl-1H-pyrazolo[4,3-e][1,2,4]triazine
por: Mojzych, Mariusz, et al.
Publicado: (2010)

Cytotoxic activity of methanolic fractions of different Marrubium spp. against melanoma cells is independent of antioxidant activity and total phenolic content
por: Kozyra, Malgorzata, et al.
Publicado: (2019)

Discovery of Potent and Selective Halogen-Substituted Imidazole-Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro via Structure-Based Design
por: Paneth, Agata, et al.
Publicado: (2019)

5,5′,6,6′-Tetramethyl-3,3′-bi-1,2,4-triazine
por: Wolińska, Ewa, et al.
Publicado: (2011)

Terminal Phenoxy Group as a Privileged Moiety of the Drug Scaffold—A Short Review of Most Recent Studies 2013–2022
por: Kozyra, Paweł, et al.
Publicado: (2022)

1,2,4-Triazine Sulfonamides: Synthesis by Sulfenamide Intermediates, In Vitro Anticancer Screening, Structural Characterization, and Molecular Docking Study
por: Branowska, Danuta, et al.
Publicado: (2020)

The Lack of Synergy between Carvedilol and the Preventive Effect of Dexrazoxane in the Model of Chronic Anthracycline-Induced Cardiomyopathy
por: Szponar, Jaroslaw, et al.
Publicado: (2023)

The Mitochondria-Independent Cytotoxic Effect of Leflunomide on RPMI-8226 Multiple Myeloma Cell Line
por: Adamczuk, Grzegorz, et al.
Publicado: (2021)

1-(3-Chlorophenyl)-3-(1-p-tolylimidazolidin-2-ylidene)urea
por: Wysocki, Waldemar, et al.
Publicado: (2008)

Design, Synthesis, Antimicrobial, and Anticancer Activities of Acridine Thiosemicarbazides Derivatives
por: Chen, Rui, et al.
Publicado: (2019)

Guanidines: Synthesis of Novel Histamine H(3)R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect
por: Staszewski, Marek, et al.
Publicado: (2023)

5,6,7,8-Tetrahydroquinolin-8-one
por: Lipińska, Teodozja M., et al.
Publicado: (2011)

Inhibition of glycolysis disrupts cellular antioxidant defense and sensitizes HepG2 cells to doxorubicin treatment
por: Korga, Agnieszka, et al.
Publicado: (2019)

Antitumor Activity and Physicochemical Properties of New Thiosemicarbazide Derivative and Its Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) Complexes
por: Rogalewicz, Bartłomiej, et al.
Publicado: (2022)

5,6,7,8-Tetrahydroquinoline 1-oxide hemihydrate
por: Karczmarzyk, Zbigniew, et al.
Publicado: (2010)

The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate
por: Kaczor, Agnieszka A., et al.
Publicado: (2013)

Synthesis, antibacterial and antiproliferative potential of some new 1-pyridinecarbonyl-4-substituted thiosemicarbazide derivatives
por: Pitucha, Monika, et al.
Publicado: (2016)

6-(2-Chlorobenzyl)-1-(4-chlorophenyl)-7-hydroxy-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one
por: Wysocki, Waldemar, et al.
Publicado: (2010)

Phytochemical Analysis and Anti-Cancer Properties of Extracts of Centaurea castriferrei Borbás & Waisb Genus of Centaurea L
por: Kubik, Joanna, et al.
Publicado: (2022)

Growth Rate and Bone Hydroxyproline Concentration in Turkeys Fed with a Silage-Composed Diet Modified with Different Diet Cation–Anion Differences (DCADs)
por: Wójcik, Marta, et al.
Publicado: (2021)

The effect of a number of H9C2 rat cardiomyocytes passage on repeatability of cytotoxicity study results
por: Witek, Piotr, et al.
Publicado: (2016)

New Coordination Compounds Based on a Pyrazine Derivative: Design, Characterization, and Biological Study
por: Climova, Alina, et al.
Publicado: (2022)

Targeting Energy Metabolism in Cancer Treatment
por: Kubik, Joanna, et al.
Publicado: (2022)

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity
por: Wróbel, Tomasz M., et al.
Publicado: (2015)

Cardioprotective Effect of Centaurea castriferrei Borbás & Waisb Extract against Doxorubicin-Induced Cardiotoxicity in H9c2 Cells
por: Humeniuk, Ewelina, et al.
Publicado: (2023)

Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis
por: Borba, Joyce Villa Verde Bastos, et al.
Publicado: (2018)

Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity
por: Korga, Agnieszka, et al.
Publicado: (2019)

Di-μ-thiosemicarbazide-κ(4) S:S-bis[bis(thiosemicarbazide-κS)copper(I)] diiodide
por: Jia, Li, et al.
Publicado: (2008)

Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
por: Korga, Agnieszka, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9atl73lg6mkif3ebld01c9ekah