Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases

Lytic Polysaccharide Monooxygenases (LPMOs) oxidatively cleave recalcitrant polysaccharides. The mechanism involves (i) reduction of the Cu, (ii) polysaccharide binding, (iii) binding of different oxygen species, and (iv) glycosidic bond cleavage. However, the complete mechanism is poorly understood...

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Detalles Bibliográficos
Autores principales: Banerjee, Sanchari, Muderspach, Sebastian J., Tandrup, Tobias, Frandsen, Kristian Erik Høpfner, Singh, Raushan K., Ipsen, Johan Ørskov, Hernández-Rollán, Cristina, Nørholm, Morten H. H., Bjerrum, Morten J., Johansen, Katja Salomon, Lo Leggio, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961595/
https://www.ncbi.nlm.nih.gov/pubmed/35204695
http://dx.doi.org/10.3390/biom12020194

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