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Spreading of Aggregated α-Synuclein in Sagittal Organotypic Mouse Brain Slices
The accumulation of α-synuclein (α-syn) in the brain plays a role in synucleinopathies and it is hypothesized to spread in a prion-like fashion between connected brain regions. In the present study, we aim to investigate this spreading in well-characterized sagittal organotypic whole brain slices ta...
Autores principales: | Uçar, Buket, Stefanova, Nadia, Humpel, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961638/ https://www.ncbi.nlm.nih.gov/pubmed/35204664 http://dx.doi.org/10.3390/biom12020163 |
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