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Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review
OBJECTIVES: Japanese encephalitis (JE) is one of the major mosquito-borne infectious diseases in the Western Pacific region, accounting for 20%–30% of mortality cases. The JE virus (JEV) seroprevalence fluctuations indicate that continuous research is important for prevention and control activities....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OMJ
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961779/ https://www.ncbi.nlm.nih.gov/pubmed/35356365 http://dx.doi.org/10.5001/omj.2021.86 |
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author | Ramli, Nur Suhada Ismail, Norayuni Mohd Zaini, Na’eemah Hayati, Firdaus Jeffree, Mohammad Saffree Abdul Rahim, Syed Sharizman Syed Hassan, Mohd Rohaizat |
author_facet | Ramli, Nur Suhada Ismail, Norayuni Mohd Zaini, Na’eemah Hayati, Firdaus Jeffree, Mohammad Saffree Abdul Rahim, Syed Sharizman Syed Hassan, Mohd Rohaizat |
author_sort | Ramli, Nur Suhada |
collection | PubMed |
description | OBJECTIVES: Japanese encephalitis (JE) is one of the major mosquito-borne infectious diseases in the Western Pacific region, accounting for 20%–30% of mortality cases. The JE virus (JEV) seroprevalence fluctuations indicate that continuous research is important for prevention and control activities. By mapping JEV seroprevalence by age stratification, the population profile for immunity and susceptibility can be identified to aid in vaccination program planning. Thus, this study aimed to determine the trend of age-specific JEV seroprevalence. METHODS: We conducted a systematic review of all studies conducted on JEV seroprevalence between 2010 and 2019. The two search engines used were PubMed and Web of Science. Eligible criteria were set, and articles were screened according to the Preferred Reporting Items for Systematic Reviews and Meta- Analyses guidelines. Three investigators cross-checked all articles assigned. Data were extracted into an Excel sheet, and results were tabulated in tables and graphs accordingly. RESULTS: Four studies from four countries (Taiwan, Sri Lanka, South Korea, and India) met the eligibility criteria. The papers showed an increasing trend of JEV seropositivity in all countries as their populations reach older age cohorts. Nonetheless, there were slight downtrend notches seen among young adults in Taiwan and India before increasing after reaching more mature ages. South Korea has the highest seroprevalence rate (97.8%–98.3%) among the compared countries. This is most likely because it was the earliest to introduce the JEV vaccine in 1967, which was later made mandatory in the early 1980s, while India has the lowest seroprevalence rate (12.9%–18.1%). Among the old vaccination-naïve population, seropositivity is commonly derived from natural infection. CONCLUSIONS: Decreases in reported JE cases are mainly due to immunization. As JEV is expected to remain in nature and the zoonotic chains, the risk of infection will persist. Hence, it is important to apply JEV vaccination protocols in national immunization programs, prioritizing young children. |
format | Online Article Text |
id | pubmed-8961779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | OMJ |
record_format | MEDLINE/PubMed |
spelling | pubmed-89617792022-03-29 Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review Ramli, Nur Suhada Ismail, Norayuni Mohd Zaini, Na’eemah Hayati, Firdaus Jeffree, Mohammad Saffree Abdul Rahim, Syed Sharizman Syed Hassan, Mohd Rohaizat Oman Med J Review Article OBJECTIVES: Japanese encephalitis (JE) is one of the major mosquito-borne infectious diseases in the Western Pacific region, accounting for 20%–30% of mortality cases. The JE virus (JEV) seroprevalence fluctuations indicate that continuous research is important for prevention and control activities. By mapping JEV seroprevalence by age stratification, the population profile for immunity and susceptibility can be identified to aid in vaccination program planning. Thus, this study aimed to determine the trend of age-specific JEV seroprevalence. METHODS: We conducted a systematic review of all studies conducted on JEV seroprevalence between 2010 and 2019. The two search engines used were PubMed and Web of Science. Eligible criteria were set, and articles were screened according to the Preferred Reporting Items for Systematic Reviews and Meta- Analyses guidelines. Three investigators cross-checked all articles assigned. Data were extracted into an Excel sheet, and results were tabulated in tables and graphs accordingly. RESULTS: Four studies from four countries (Taiwan, Sri Lanka, South Korea, and India) met the eligibility criteria. The papers showed an increasing trend of JEV seropositivity in all countries as their populations reach older age cohorts. Nonetheless, there were slight downtrend notches seen among young adults in Taiwan and India before increasing after reaching more mature ages. South Korea has the highest seroprevalence rate (97.8%–98.3%) among the compared countries. This is most likely because it was the earliest to introduce the JEV vaccine in 1967, which was later made mandatory in the early 1980s, while India has the lowest seroprevalence rate (12.9%–18.1%). Among the old vaccination-naïve population, seropositivity is commonly derived from natural infection. CONCLUSIONS: Decreases in reported JE cases are mainly due to immunization. As JEV is expected to remain in nature and the zoonotic chains, the risk of infection will persist. Hence, it is important to apply JEV vaccination protocols in national immunization programs, prioritizing young children. OMJ 2022-03-22 /pmc/articles/PMC8961779/ /pubmed/35356365 http://dx.doi.org/10.5001/omj.2021.86 Text en The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC) 4.0 License. http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Review Article Ramli, Nur Suhada Ismail, Norayuni Mohd Zaini, Na’eemah Hayati, Firdaus Jeffree, Mohammad Saffree Abdul Rahim, Syed Sharizman Syed Hassan, Mohd Rohaizat Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title | Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title_full | Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title_fullStr | Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title_full_unstemmed | Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title_short | Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review |
title_sort | seroepidemiological studies on japanese encephalitis: a systematic review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961779/ https://www.ncbi.nlm.nih.gov/pubmed/35356365 http://dx.doi.org/10.5001/omj.2021.86 |
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