Cargando…
Bone-Specific Enhancement of Antibody Therapy for Breast Cancer Metastasis to Bone
[Image: see text] Despite the rapid evolution of therapeutic antibodies, their clinical efficacy in the treatment of bone tumors is hampered due to the inadequate pharmacokinetics and poor bone tissue accessibility of these large macromolecules. Here, we show that engineering therapeutic antibodies...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961797/ https://www.ncbi.nlm.nih.gov/pubmed/35355817 http://dx.doi.org/10.1021/acscentsci.1c01024 |