Bone-Specific Enhancement of Antibody Therapy for Breast Cancer Metastasis to Bone

[Image: see text] Despite the rapid evolution of therapeutic antibodies, their clinical efficacy in the treatment of bone tumors is hampered due to the inadequate pharmacokinetics and poor bone tissue accessibility of these large macromolecules. Here, we show that engineering therapeutic antibodies...

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Detalles Bibliográficos
Autores principales: Tian, Zeru, Yu, Chenfei, Zhang, Weijie, Wu, Kuan-Lin, Wang, Chenhang, Gupta, Ruchi, Xu, Zhan, Wu, Ling, Chen, Yuda, Zhang, Xiang H.-F., Xiao, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961797/
https://www.ncbi.nlm.nih.gov/pubmed/35355817
http://dx.doi.org/10.1021/acscentsci.1c01024

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