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RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF-κB signaling and ameliorates murine colitis

BACKGROUND: Ulcerative colitis (UC) is a common inflammatory bowel disease, during which cell necroptosis plays key roles in driving inflammation initiation and aggravation. Previous studies reported Receptor Interacting Protein Kinase 3 (RIP3)-mediated necroptosis in multiple diseases, and RIP3 pro...

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Detalles Bibliográficos
Autores principales:	Duan, Chaoqin, Xu, Xi, Lu, Xiaoyi, Wang, Ling, Lu, Zhongkai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8961930/ https://www.ncbi.nlm.nih.gov/pubmed/35346043 http://dx.doi.org/10.1186/s12876-022-02208-x

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