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Investigating the role of peptides in effective therapies against cancer

Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental innovations in traditional diagnosis and therapy are necessary. Peptides can be very helpful in this regard due to their potential and diversity....

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Detalles Bibliográficos
Autores principales: Naeimi, Reza, Bahmani, Asrin, Afshar, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962089/
https://www.ncbi.nlm.nih.gov/pubmed/35346211
http://dx.doi.org/10.1186/s12935-022-02553-7
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author Naeimi, Reza
Bahmani, Asrin
Afshar, Saeid
author_facet Naeimi, Reza
Bahmani, Asrin
Afshar, Saeid
author_sort Naeimi, Reza
collection PubMed
description Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental innovations in traditional diagnosis and therapy are necessary. Peptides can be very helpful in this regard due to their potential and diversity. To enhance the therapeutic potential of peptides, their limitations must be properly identified and their structures engineered and modified for higher efficiency. Promoting the bioavailability and stability of peptides is one of the main concerns. Peptides can also be effective in different areas of targeting, alone or with the help of other therapeutic agents. There has been a lot of research in this area, and the potential for variability of peptides will continue to improve this process. Another promising area in which peptides can help treat cancer is peptide vaccines, which are undergoing promising research, and high throughput technologies can lead to fundamental changes in this area. Peptides have been effective in almost all areas of cancer treatment, and some have even gone through clinical phases. However, many barriers need to be overcome to reach the desired point. The purpose of this review is to evaluate the mechanisms associated with peptides in the diagnosis and treatment of cancer. Therefore, related studies in this area will be discussed.
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spelling pubmed-89620892022-03-30 Investigating the role of peptides in effective therapies against cancer Naeimi, Reza Bahmani, Asrin Afshar, Saeid Cancer Cell Int Review Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental innovations in traditional diagnosis and therapy are necessary. Peptides can be very helpful in this regard due to their potential and diversity. To enhance the therapeutic potential of peptides, their limitations must be properly identified and their structures engineered and modified for higher efficiency. Promoting the bioavailability and stability of peptides is one of the main concerns. Peptides can also be effective in different areas of targeting, alone or with the help of other therapeutic agents. There has been a lot of research in this area, and the potential for variability of peptides will continue to improve this process. Another promising area in which peptides can help treat cancer is peptide vaccines, which are undergoing promising research, and high throughput technologies can lead to fundamental changes in this area. Peptides have been effective in almost all areas of cancer treatment, and some have even gone through clinical phases. However, many barriers need to be overcome to reach the desired point. The purpose of this review is to evaluate the mechanisms associated with peptides in the diagnosis and treatment of cancer. Therefore, related studies in this area will be discussed. BioMed Central 2022-03-27 /pmc/articles/PMC8962089/ /pubmed/35346211 http://dx.doi.org/10.1186/s12935-022-02553-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Naeimi, Reza
Bahmani, Asrin
Afshar, Saeid
Investigating the role of peptides in effective therapies against cancer
title Investigating the role of peptides in effective therapies against cancer
title_full Investigating the role of peptides in effective therapies against cancer
title_fullStr Investigating the role of peptides in effective therapies against cancer
title_full_unstemmed Investigating the role of peptides in effective therapies against cancer
title_short Investigating the role of peptides in effective therapies against cancer
title_sort investigating the role of peptides in effective therapies against cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962089/
https://www.ncbi.nlm.nih.gov/pubmed/35346211
http://dx.doi.org/10.1186/s12935-022-02553-7
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