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PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p

BACKGROUND: Emerging evidence has demonstrated that RNA-binding protein dysregulation is involved in esophageal squamous cell carcinoma (ESCC) progression. However, the role of poly (A) binding protein cytoplasmic 1 (PABPC1) in ESCC is unclear. We therefore aimed to explore the functions and potenti...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Chen, Chuangzhen, Liu, Zhaoyong, Guo, Huancheng, Lu, Weiqing, Hu, Wang, Lin, Zhixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962095/
https://www.ncbi.nlm.nih.gov/pubmed/35346324
http://dx.doi.org/10.1186/s13046-022-02339-9