Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications

BACKGROUND: The retina, as part of the central nervous system (CNS) with limited capacity for self-reparation and regeneration in mammals, is under cumulative environmental stress due to high-energy demands and rapid protein turnover. These stressors disrupt the cellular protein and metabolic homeos...

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Detalles Bibliográficos
Autores principales: McLaughlin, Todd, Medina, Andy, Perkins, Jacob, Yera, Maria, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962104/
https://www.ncbi.nlm.nih.gov/pubmed/35346303
http://dx.doi.org/10.1186/s13024-022-00528-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962104/
https://www.ncbi.nlm.nih.gov/pubmed/35346303
http://dx.doi.org/10.1186/s13024-022-00528-w

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