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Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications

BACKGROUND: The retina, as part of the central nervous system (CNS) with limited capacity for self-reparation and regeneration in mammals, is under cumulative environmental stress due to high-energy demands and rapid protein turnover. These stressors disrupt the cellular protein and metabolic homeos...

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Detalles Bibliográficos
Autores principales:	McLaughlin, Todd, Medina, Andy, Perkins, Jacob, Yera, Maria, Wang, Joshua J., Zhang, Sarah X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962104/ https://www.ncbi.nlm.nih.gov/pubmed/35346303 http://dx.doi.org/10.1186/s13024-022-00528-w

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