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Co-targeting WIP1 and PARP induces synthetic lethality in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most fatal cancers. Due to limited strategies for effective treatments, patients with advanced HCC have a very poor prognosis. This study aims to identify new insights in HCC to develop novel strategies for HCC management. METHODS: The role of...

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Detalles Bibliográficos
Autores principales: Chen, Miaoqin, Wang, Weikai, Hu, Shiman, Tong, Yifan, Li, Yiling, Wei, Qi, Yu, Lei, Zhu, Liyuan, Zhu, Yiran, Liu, Leiming, Ju, Zhenyu, Wang, Xian, Jin, Hongchuan, Feng, Lifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962187/
https://www.ncbi.nlm.nih.gov/pubmed/35346236
http://dx.doi.org/10.1186/s12964-022-00850-2