Cargando…
CIGB-300-Regulated Proteome Reveals Common and Tailored Response Patterns of AML Cells to CK2 Inhibition
Protein kinase CK2 is a highly pleiotropic and ubiquitously expressed Ser/Thr kinase with instrumental roles in normal and pathological states, including neoplastic phenotype in solid tumor and hematological malignancies. In line with previous reports, CK2 has been suggested as an attractive prognos...
Autores principales: | Rosales, Mauro, Rodríguez-Ulloa, Arielis, Pérez, George V., Besada, Vladimir, Soto, Thalia, Ramos, Yassel, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Yang, Ke, Perera, Yasser, Perea, Silvio E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962202/ https://www.ncbi.nlm.nih.gov/pubmed/35359604 http://dx.doi.org/10.3389/fmolb.2022.834814 |
Ejemplares similares
-
Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300
por: Rosales, Mauro, et al.
Publicado: (2021) -
Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945
por: Rosales, Mauro, et al.
Publicado: (2021) -
CIGB-300 Anticancer Peptide Differentially Interacts with CK2 Subunits and Regulates Specific Signaling Mediators in a Highly Sensitive Large Cell Lung Carcinoma Cell Model
por: Pérez, George V., et al.
Publicado: (2022) -
Gene expression profiling unveils the temporal dynamics of CIGB-300-regulated transcriptome in AML cell lines
por: Vázquez-Blomquist, Dania, et al.
Publicado: (2023) -
Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization
por: Gottardo, Maria F., et al.
Publicado: (2020)