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Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM

BACKGROUND: Clinical studies have shown that the efficacy of programmed cell death receptor-1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors on glioblastoma (GBM) is much lower than what is expected because of the low immunogenicity of GBM. Ferroptosis of cancer cells can induce the maturati...

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Detalles Bibliográficos
Autores principales: Liu, Bao, Ji, Qifeng, Cheng, Ying, Liu, Miao, Zhang, Bangle, Mei, Qibing, Liu, Daozhou, Zhou, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962245/
https://www.ncbi.nlm.nih.gov/pubmed/35351131
http://dx.doi.org/10.1186/s12951-022-01360-6