Cargando…

Maternal Metabolic State and Fetal Sex and Genotype Modulate Methylation of the Serotonin Receptor Type 2A Gene (HTR2A) in the Human Placenta

The serotonin receptor 2A gene (HTR2A) is a strong candidate for the fetal programming of future behavior and metabolism. Maternal obesity and gestational diabetes mellitus (GDM) have been associated with an increased risk of metabolic and psychological problems in offspring. We tested the hypothesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horvatiček, Marina, Perić, Maja, Bečeheli, Ivona, Klasić, Marija, Žutić, Maja, Kesić, Maja, Desoye, Gernot, Nakić Radoš, Sandra, Ivanišević, Marina, Hranilovic, Dubravka, Štefulj, Jasminka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962258/ https://www.ncbi.nlm.nih.gov/pubmed/35203678 http://dx.doi.org/10.3390/biomedicines10020467

Ejemplares similares

Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus
por: Blazevic, Sofia, et al.
Publicado: (2017)

Serotonin system in the human placenta – the knowns and unknowns
por: Perić, Maja, et al.
Publicado: (2022)

Differential Serotonin Uptake Mechanisms at the Human Maternal–Fetal Interface
por: Baković, Petra, et al.
Publicado: (2021)

Glucose, Insulin and Oxygen Modulate Expression of Serotonin-Regulating Genes in Human First-Trimester Trophoblast Cell Line ACH-3P
por: Perić, Maja, et al.
Publicado: (2023)

Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis
por: Kesić, Maja, et al.
Publicado: (2020)

Editorial: Developmental Abnormalities of Serotonin Homeostasis in Behavioral and Metabolic Disorders: From Epigenetic Mechanisms to Protein Function
por: Hranilovic, Dubravka, et al.
Publicado: (2021)

Metabolic Disturbances in Rat Sublines with Constitutionally Altered Serotonin Homeostasis
por: Kesić, Maja, et al.
Publicado: (2021)

Metabolic and Molecular Response to High-Fat Diet Differs between Rats with Constitutionally High and Low Serotonin Tone
por: Baković, Petra, et al.
Publicado: (2023)

Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model
por: Kesić, Maja, et al.
Publicado: (2021)

Constitutive Serotonin Tone as a Modulator of Brown Adipose Tissue Thermogenesis: A Rat Study
por: Kesić, Maja, et al.
Publicado: (2023)

The effect of chronic fluoxetine administration on anxiety-like behavior and expression of 5-HT-related proteins in rats with constitutively altered 5-HT homeostasis
por: Kesić, Maja, et al.
Publicado: (2012)

HTR1A, HTR1B, HTR2A, HTR2C and HTR6 Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia
por: Grubor, Mirko, et al.
Publicado: (2020)

SLC6A3, HTR2C and HTR6 Gene Polymorphisms and the Risk of Haloperidol-Induced Parkinsonism
por: Nedic Erjavec, Gordana, et al.
Publicado: (2022)

Pregnancy in Patients with Type One Diabetes Mellitus Treated with Continuous Subcutaneous Insulin Infusion—Preconception Basal Insulin Dose as a Potential Risk Factor for Fetal Overgrowth?
por: Lekšić, Gloria, et al.
Publicado: (2020)

Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study
por: Leksic, Gloria, et al.
Publicado: (2022)

N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus
por: Delmis, Josip, et al.
Publicado: (2021)

Supplementation of EPA and DHA in pregnant women with type 1 diabetes mellitus
por: Ivanisevic, Marina, et al.
Publicado: (2021)

Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma
por: Konjevod, Marcela, et al.
Publicado: (2023)

Ambulatory Glucose Profile Changes During Pregnancy in Women With Type 1 Diabetes Using Intermittently Scanned Continuous Glucose Monitoring Empowered by Personalized Education
por: Baretić, Maja, et al.
Publicado: (2023)

Type 1 Diabetes Mellitus and the First Trimester Placenta: Hyperglycemia-Induced Effects on Trophoblast Proliferation, Cell Cycle Regulators, and Invasion
por: Majali-Martinez, Alejandro, et al.
Publicado: (2021)

Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system
por: Josipović, Goran, et al.
Publicado: (2019)

The discovery, structure, and function of 5-HTR1E serotonin receptor
por: Sharma, Vinay Kumar, et al.
Publicado: (2023)

Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population
por: Yücel, Yavuz, et al.
Publicado: (2016)

Metalloprotease Dependent Release of Placenta Derived Fractalkine
por: Siwetz, Monika, et al.
Publicado: (2014)

THE EFFECT OF DAILY PHYSICAL ACTIVITY ON THE ACTIVITY OF INFLAMMATORY BOWEL DISEASES IN THERAPY-FREE PATIENTS
por: Holik, Dubravka, et al.
Publicado: (2019)

Acquired hemophilia A secondary to SARS-CoV-2 pneumonia: a case report
por: Nikolina, Brkić, et al.
Publicado: (2022)

Deleterious Effects of Mycotoxin Combinations Involving Ochratoxin A
por: Klarić, Maja Šegvić, et al.
Publicado: (2013)

THE ROLE OF FREQUENCY DOUBLING TECHNOLOGY PERIMETRY IN EARLY DETECTION OF DIABETIC RETINOPATHY
por: Bradvica, Mario, et al.
Publicado: (2020)

Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons
por: Ruble, Cara L., et al.
Publicado: (2016)

Population-based study of genetic variation in individuals with autism spectrum disorders from Croatia
por: Wang, Li-San, et al.
Publicado: (2010)

Constitutively Elevated Blood Serotonin Is Associated with Bone Loss and Type 2 Diabetes in Rats
por: Erjavec, Igor, et al.
Publicado: (2016)

Evaluation of serotonin receptors (5HTR2A and 5HTR3A) mRNA expression changes in tumor of breast cancer patients
por: Olfati, Zahra, et al.
Publicado: (2020)

Clinical practice guidelines with recommendations for peripartum depression: A European systematic review
por: Motrico, Emma, et al.
Publicado: (2022)

Major Aortic Reconstruction with the Replacement of Supra-Aortic Branches: Successful Surgical Treatment of Takayasu Arteritis Initially Presented as Congestive Heart Failure
por: Stojanovic, Maja, et al.
Publicado: (2021)

Ochratoxin A Contamination of Food from Croatia
por: Peraica, Maja, et al.
Publicado: (2010)

Variable neurodevelopmental and morphological phenotypes of carriers with 12q12 duplications
por: Myers, Lynnea, et al.
Publicado: (2019)

Transient Serotonin Toxicity Evoked by Combination of Electroconvulsive Therapy and Fluoxetine
por: Klysner, René, et al.
Publicado: (2014)

Exploring Evolutionary and Transmission Dynamics of HIV Epidemic in Serbia: Bridging Socio-Demographic With Phylogenetic Approach
por: Jovanović, Luka, et al.
Publicado: (2019)

Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer
por: Qin, Xuan, et al.
Publicado: (2021)

Characterization of serotonin-5-HTR1E signaling pathways and its role in cell survival
por: Sharma, Vinay Kumar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ioeogfcp6a3nrif2m1sf1rn84d