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Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties

Herein we report on the preparation of a bioactive glass (BAG)-based photocurable resin for the additive manufacturing of BAG scaffolds with high filler loadings. The preparation of glass/ceramics resins for stereolithography with high filler loading is always a challenge, especially for fillers wit...

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Autores principales: Chen, Qirong, Schmidt, Franziska, Görke, Oliver, Asif, Anila, Weinhold, Joachim, Aghaei, Erfan, Rehman, Ihtesham ur, Gurlo, Aleksander, Shah, Asma Tufail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962265/
https://www.ncbi.nlm.nih.gov/pubmed/35203606
http://dx.doi.org/10.3390/biomedicines10020395
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author Chen, Qirong
Schmidt, Franziska
Görke, Oliver
Asif, Anila
Weinhold, Joachim
Aghaei, Erfan
Rehman, Ihtesham ur
Gurlo, Aleksander
Shah, Asma Tufail
author_facet Chen, Qirong
Schmidt, Franziska
Görke, Oliver
Asif, Anila
Weinhold, Joachim
Aghaei, Erfan
Rehman, Ihtesham ur
Gurlo, Aleksander
Shah, Asma Tufail
author_sort Chen, Qirong
collection PubMed
description Herein we report on the preparation of a bioactive glass (BAG)-based photocurable resin for the additive manufacturing of BAG scaffolds with high filler loadings. The preparation of glass/ceramics resins for stereolithography with high filler loading is always a challenge, especially for fillers with a high refractive index variance. Various photocurable resin compositions with and without bioactive glass fillers have been investigated to see the influence of bioactive glass on physical properties of the resin and resulting green body. The effect of concentration of monomers, reactive diluent, light absorber (Sudan orange G dye), photoinitiator (PI), non-reactive diluent, and fillers (BAG) on rheology and photocuring behavior of the resin and tomography of the resulting 3D structures have been investigated. The BAG contents affect the rheology of resin and influence the rate of the polymerization reaction. The resin compositions with 55–60% BAG, 10% PEG-200 (diluent), 1% of PI and 0.015% of the dye were found to be suitable compositions for the stereolithographic fabrication. A higher percentage of PI caused over-curing, while a higher amount of dye decreased the cure depth of the resin. The micro-computed tomography (µ-CT) and scanning electron microscopic (SEM) images of the resulting green bodies display a relatively dense glass scaffold without any visible cracks and good interlayer connection and surface finishing. These properties play an important role in the mechanical behavior of 3D scaffolds. This study will be helpful to prepare high density glass/ceramic slurries and optimize their printing properties.
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spelling pubmed-89622652022-03-30 Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties Chen, Qirong Schmidt, Franziska Görke, Oliver Asif, Anila Weinhold, Joachim Aghaei, Erfan Rehman, Ihtesham ur Gurlo, Aleksander Shah, Asma Tufail Biomedicines Article Herein we report on the preparation of a bioactive glass (BAG)-based photocurable resin for the additive manufacturing of BAG scaffolds with high filler loadings. The preparation of glass/ceramics resins for stereolithography with high filler loading is always a challenge, especially for fillers with a high refractive index variance. Various photocurable resin compositions with and without bioactive glass fillers have been investigated to see the influence of bioactive glass on physical properties of the resin and resulting green body. The effect of concentration of monomers, reactive diluent, light absorber (Sudan orange G dye), photoinitiator (PI), non-reactive diluent, and fillers (BAG) on rheology and photocuring behavior of the resin and tomography of the resulting 3D structures have been investigated. The BAG contents affect the rheology of resin and influence the rate of the polymerization reaction. The resin compositions with 55–60% BAG, 10% PEG-200 (diluent), 1% of PI and 0.015% of the dye were found to be suitable compositions for the stereolithographic fabrication. A higher percentage of PI caused over-curing, while a higher amount of dye decreased the cure depth of the resin. The micro-computed tomography (µ-CT) and scanning electron microscopic (SEM) images of the resulting green bodies display a relatively dense glass scaffold without any visible cracks and good interlayer connection and surface finishing. These properties play an important role in the mechanical behavior of 3D scaffolds. This study will be helpful to prepare high density glass/ceramic slurries and optimize their printing properties. MDPI 2022-02-07 /pmc/articles/PMC8962265/ /pubmed/35203606 http://dx.doi.org/10.3390/biomedicines10020395 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Qirong
Schmidt, Franziska
Görke, Oliver
Asif, Anila
Weinhold, Joachim
Aghaei, Erfan
Rehman, Ihtesham ur
Gurlo, Aleksander
Shah, Asma Tufail
Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title_full Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title_fullStr Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title_full_unstemmed Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title_short Ceramic Stereolithography of Bioactive Glasses: Influence of Resin Composition on Curing Behavior and Green Body Properties
title_sort ceramic stereolithography of bioactive glasses: influence of resin composition on curing behavior and green body properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962265/
https://www.ncbi.nlm.nih.gov/pubmed/35203606
http://dx.doi.org/10.3390/biomedicines10020395
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