LL-37 and Double-Stranded RNA Synergistically Upregulate Bronchial Epithelial TLR3 Involving Enhanced Import of Double-Stranded RNA and Downstream TLR3 Signaling

The human host defense peptide LL-37 influences double-stranded RNA signaling, but this process is not well understood. Here, we investigate synergistic actions of LL-37 and synthetic double-stranded RNA (poly I:C) on toll-like receptor 3 (TLR3) expression and signaling, and examine underlying mecha...

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Detalles Bibliográficos
Autores principales: Bodahl, Sara, Cerps, Samuel, Uller, Lena, Nilsson, Bengt-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962275/
https://www.ncbi.nlm.nih.gov/pubmed/35203701
http://dx.doi.org/10.3390/biomedicines10020492

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