Implications of Heterogeneity of Epithelial-Mesenchymal States in Acromegaly Therapeutic Pharmacologic Response

Acromegaly is caused by excess growth hormone (GH) produced by a pituitary tumor. First-generation somatostatin receptor ligands (SRLs) are the first-line treatment. Several studies have linked E-cadherin loss and epithelial-mesenchymal transition (EMT) with resistance to SRLs. Our aim was to study...

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Detalles Bibliográficos
Autores principales: Gil, Joan, Marques-Pamies, Montserrat, Valassi, Elena, García-Martínez, Araceli, Serra, Guillermo, Hostalot, Cristina, Fajardo-Montañana, Carmen, Carrato, Cristina, Bernabeu, Ignacio, Marazuela, Mónica, Rodríguez-Lloveras, Helena, Cámara, Rosa, Salinas, Isabel, Lamas, Cristina, Biagetti, Betina, Simó-Servat, Andreu, Webb, Susan M., Picó, Antonio, Jordà, Mireia, Puig-Domingo, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962441/
https://www.ncbi.nlm.nih.gov/pubmed/35203668
http://dx.doi.org/10.3390/biomedicines10020460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962441/
https://www.ncbi.nlm.nih.gov/pubmed/35203668
http://dx.doi.org/10.3390/biomedicines10020460

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