Cargando…

Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder

BACKGROUND: Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are commonly reported co-occurring mental health consequences of psychological trauma exposure. The disorders have high genetic overlap. Trauma is a complex phenotype but research suggests that trauma sensitivity ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mundy, Jessica, Hübel, Christopher, Gelernter, Joel, Levey, Daniel, Murray, Robin M., Skelton, Megan, Stein, Murray B., Vassos, Evangelos, Breen, Gerome, Coleman, Jonathan R. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962503/ https://www.ncbi.nlm.nih.gov/pubmed/34085609 http://dx.doi.org/10.1017/S0033291721000830

Ejemplares similares

Genetic Decomposition of the Heritable Component of Reported Childhood Maltreatment
por: ter Kuile, Abigail R., et al.
Publicado: (2023)

Research priorities in psychiatric genetic counselling: how to talk to children and adolescents about genetics and psychiatric disorders
por: Mundy, Jessica, et al.
Publicado: (2022)

Dissecting the heterogeneity of posttraumatic stress disorder: differences in polygenic risk, stress exposures, and course of PTSD subtypes
por: Campbell-Sills, Laura, et al.
Publicado: (2022)

Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder
por: Wendt, Frank R, et al.
Publicado: (2022)

Epigenetics in eating disorders: a systematic review
por: Hübel, Christopher, et al.
Publicado: (2018)

Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality
por: Wendt, Frank R., et al.
Publicado: (2021)

Genome-wide association analyses of posttraumatic stress disorder and its symptom subdomains in the Million Veteran Program
por: Stein, Murray B., et al.
Publicado: (2021)

Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study
por: Polimanti, Renato, et al.
Publicado: (2019)

Psychological trauma, posttraumatic stress disorder and trauma-related depression: A mini-review
por: Wang, Shi-Kai, et al.
Publicado: (2023)

Cardiovascular and psychological responses to voluntary recall of trauma in posttraumatic stress disorder
por: Chou, Chia-Ying, et al.
Publicado: (2018)

The overlap between complex posttraumatic stress disorder and borderline personality disorder
por: García, C. Álvarez, et al.
Publicado: (2021)

Association between polygenic propensity for psychiatric disorders and nutrient intake
por: Hunjan, Avina K., et al.
Publicado: (2021)

Posttraumatic stress disorder and the nature of trauma
por: van der Kolk, Bessel
Publicado: (2000)

No Evidence for Passive Gene-Environment Correlation or the Influence of Genetic Risk for Psychiatric Disorders on Adult Body Composition via the Adoption Design
por: Hunjan, Avina K., et al.
Publicado: (2020)

Psychological trauma and posttraumatic stress disorder: risk factors and associations with birth outcomes in the Drakenstein Child Health Study
por: Koen, Nastassja, et al.
Publicado: (2016)

Sociodemographic factors associated with treatment-seeking and treatment receipt: cross-sectional analysis of UK Biobank participants with lifetime generalised anxiety or major depressive disorder
por: Rayner, Christopher, et al.
Publicado: (2021)

Editorial: Trauma, Psychosis and Posttraumatic Stress Disorder
por: Hardy, Kate V., et al.
Publicado: (2017)

Assessing the Evidence for Causal Associations Between Body Mass Index, C-Reactive Protein, Depression, and Reported Trauma Using Mendelian Randomization
por: Palmos, Alish B., et al.
Publicado: (2022)

An Examination of Differences in Psychological Resilience between Social Anxiety Disorder and Posttraumatic Stress Disorder in the Context of Early Childhood Trauma
por: Marx, Melanie, et al.
Publicado: (2017)

Trauma and Posttraumatic Stress Disorder (PTSD) in Patients with Schizophrenia or Schizoaffective Disorder
por: Lommen, Miriam J. J., et al.
Publicado: (2009)

Feasibility of Identifying Eligible Trauma Patients for Posttraumatic Stress Disorder Intervention
por: Malcoun, Emily, et al.
Publicado: (2010)

Psychological trauma and evidence for enhanced vulnerability for posttraumatic stress disorder through previous trauma among West Nile refugees
por: Neuner, Frank, et al.
Publicado: (2004)

Eating disorder symptoms and their associations with anthropometric and psychiatric polygenic scores
por: Abdulkadir, Mohamed, et al.
Publicado: (2022)

Evidence of symptom profiles consistent with posttraumatic stress disorder and complex posttraumatic stress disorder in different trauma samples
por: Elklit, Ask, et al.
Publicado: (2014)

Genetic associations with suicide attempt severity and genetic overlap with major depression
por: Levey, Daniel F., et al.
Publicado: (2019)

Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder
por: Gaspar, Héléna A., et al.
Publicado: (2019)

Childhood Trauma, Posttraumatic Stress Disorder, and Alcohol Dependence
por: Brady, Kathleen T., et al.
Publicado: (2012)

Prevalence of posttraumatic stress disorder in acute trauma patients
por: Joseph, Noah M., et al.
Publicado: (2020)

An analysis of early developmental trauma in social anxiety disorder and posttraumatic stress disorder
por: Bishop, Melanie, et al.
Publicado: (2014)

Trauma exposure, posttraumatic stress disorder and the effect of explanatory variables in paramedic trainees
por: Fjeldheim, Celine B, et al.
Publicado: (2014)

Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder
por: Deak, Joseph D., et al.
Publicado: (2022)

Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
por: Lynall, Mary-Ellen, et al.
Publicado: (2022)

Understanding and Treating Unwanted Trauma Memories in Posttraumatic Stress Disorder
por: Ehlers, Anke
Publicado: (2010)

Editorial: Molecular Mechanisms in Stress and Trauma Related Disorders
por: Zannas, Anthony S., et al.
Publicado: (2020)

When Nowhere Is Safe: Interpersonal Trauma and Attachment Adversity as Antecedents of Posttraumatic Stress Disorder and Developmental Trauma Disorder
por: Spinazzola, Joseph, et al.
Publicado: (2018)

Profiles of Childhood Trauma in Women With Substance Use Disorders and Comorbid Posttraumatic Stress Disorders
por: Lotzin, Annett, et al.
Publicado: (2019)

Patient characteristics associated with retrospectively self-reported treatment outcomes following psychological therapy for anxiety or depressive disorders - a cohort of GLAD study participants
por: Rayner, Christopher, et al.
Publicado: (2022)

One size does not fit all. Genomics differentiates among anorexia nervosa, bulimia nervosa, and binge‐eating disorder
por: Hübel, Christopher, et al.
Publicado: (2021)

Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder
por: Wingo, Thomas S., et al.
Publicado: (2022)

Drug Targetor: a web interface to investigate the human druggome for over 500 phenotypes
por: Gaspar, Héléna A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0q2omebu2qiola00jhan0k5k0e